P blood group phenotype, proteus antibody titres, and rheumatoid arthritis.

Antibody producing capacity to the bacteriophage phi X174 in rheumatoid arthritis.

A study of antibody production in response to a primary immunogen, the bacteriophage phi X174, was performed in 27 patients with rheumatoid arthritis and 15 controls. All patients produced a primary (IgM) response to initial immunisation. The frequency distribution of peak antibody titres after secondary immunisation showed a marked difference between the patients and controls, with 10 patients...

Elevated levels of IgM and IgA antibodies to Proteus mirabilis and IgM antibodies to Escherichia coli are associated with early rheumatoid factor (RF)-positive rheumatoid arthritis.

OBJECTIVE Antibodies to Proteus mirabilis were previously detected in patients with established rheumatoid arthritis (RA). We examined the prevalence of antibodies to P. mirabilis and their associations with RA in early synovitis patients. METHODS Two hundred and forty-six patients with inflammatory arthritis for less than 1 yr were prospectively evaluated for 1 yr. Of these patients, 30% had...

Similar anti-Proteus mirabilis titres in P1 positive and P1 negative individuals with rheumatoid arthritis.

Comparison of complement-fixing antibody titres in patients with rheumatoid arthritis and matched controls.

Many of the clinical findings in rheumatoid arthritis are consistent with an infectious aetiology. Direct methods of demonstrating infectious agents in rheumatoid tissues have given apparently conflicting results (Bartholomew, 1967; Duthie, Stewart, Alexander, and Dayhoff, 1967; Sharp, 1970). Indirect evidence, namely the demonstration of differences in titres of antibodies against different an...

Rubella antibody levels in juvenile rheumatoid arthritis.

Increased rubella antibody titres have been reported in patients with juvenile rheumatoid arthritis (JRA) and it has been suggested that rubella virus may be of importance in the aetiology or pathogenesis of the disease. In the present study, rubella and rubeola antibody titres in 85 patients with JRA were compared to age- and sex-matched controls. 41% of the patients did not have rubella antib...